Speakers:

Douglas ReesDouglas Rees (California Institute of Technology; HHMI) is a central figure in the determination of membrane protein structure by x-ray crystallography, notably transport proteins and mechanosensitive channels.  He is a member of the National Academy of Sciences and the American Academy of Arts & Sciences. Dr. Rees was a Searle Foundation Scholar and Alfred P. Sloan Research Scholar.  He received a National Science Foundation Presidential Young Investigator Award, the Protein Society Dorothy Crowfoot Hodgkin Award and ASCIT Excellence in Teaching Award from the Associated Students of Cal Tech.

Frederick SachsFredrick Sachs (State University of New York, Buffalo) discovered mechanosensitive ion channels pioneering the contemporary studies of cellular sensing of mechanical forces.  His laboratory utilizes many biophysical techniques including patch clamping, atomic force microscopy, molecular biology, protein chemistry, computer software and instrument hardware and optical imaging. He also holds several patents.  He has been honored by the Biophysical Society’s Cole Award, a Fogarty Fellowship and various SUNY awards. He is currently supported by NIH, DOD, Children’s Guild and the UB Center for Advanced Technology.

Kenton SwartzKenton Swartz (NINDS/NIH) has made important contributions to our understanding of voltage-gated ion channels, particularly potassium channels.  He utilizes multiple approaches including biophysical and computational ones.  Dr. Swartz characterizes and utilizes toxins from organisms such as spiders to study these channels.  He is a past President of the Society of General Physiologists, Associate Editor of The Journal of General Physiology and recipient of several NIH awards including a NIH Director’s Award for Individual Scientific Achievement.

Rachelle GaudetRachelle Gaudet (Harvard) uses x-ray crystallography and biochemistry to provide important insights into the molecular mechanisms of temperature and pain sensing by a family of ion channels as well as antigen presentation by an ATP-powered transport protein.  She received an American Heart Association Development Grant, a March of Dimes Basil O’Conner Starter Scholar Award, an American Cancer Society Scholar award, a McKnight Scholar Award and a Joseph Klingenstein Fellowship.  She recently became a Fellow of the American Association for the Advancement of Science.

Linda RandallLinda Randall (University of Missouri) pioneered biochemical study of protein translocation across bacterial membranes and was the first to implicate maintenance of an unfolded state and chaperones in protein export.  Dr. Randall is a member of the National Academy of Sciences and the American Academy of Arts & Sciences, and a Fellow of the American Academy of Microbiology and the American Association for the Advancement of Science.  She received the Eli Lilly Award in Microbiology and the Protein Society’s Parke Davis Award.

Gerald HazelbauerGerald Hazelbauer (University of Missouri) has been a key contributor in identifying molecular mechanisms of transmembrane sensory signaling, focusing on bacterial chemoreceptor proteins.   He is a Fellow of the American Academy of Microbiology and the American Association for the Advancement of Science.  Dr. Hazelbauer received an Alfred P. Sloan Research Fellowship, McKnight Neuroscience Development Award, American Cancer Society Faculty Research Award and NIH MERIT Award.  He served as an officer of the Protein Society.

TC HwangTzyh-Chang (TC) Hwang (University of Missouri) studies multiple aspects of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR), an ATP-gated ion channel that when disrupted results in the disease.  He serves on the editorial boards of the Journal of General Physiology and the Biophysical Journal and has been a consultant for Cystic Fibrosis Foundation Therapeutics.    Dr. Hwang has been honored by the Society of General Physiologists’ Paul Cranefield Award and honorary visiting professorships at Osaka Medical College and Xian Jaotong University.

 


Sponsors: Mizzou Advantage
Biophysical Society
Chancellor’s Distinguished Visitors Program
Dalton Cardiovascular Research Center
Mizzou Advantage
MU Department of Biochemistry Biophysical
MU Department of Biological Engineering
MU Division of Biological Sciences
MU Department of Medical Pharmacology and Physiology
MU Department of Physics
  Fisher Scientific